OverviewGlomerulonephritis (gloe-MER-u-loe-nuh-FRY-tis) is inflammation of the tiny filters in the kidneys (glomeruli). The excess fluid and waste that glomeruli (gloe-MER-u-lie) remove from the bloodstream exit the body as urine. Glomerulonephritis can come on suddenly (acute) or gradually (chronic). Show
Glomerulonephritis occurs on its own or as part of another disease, such as lupus or diabetes. Severe or prolonged inflammation associated with glomerulonephritis can damage the kidneys. Treatment depends on the type of glomerulonephritis you have. SymptomsSigns and symptoms of glomerulonephritis may vary depending on whether you have the acute or chronic form and the cause. You may notice no symptoms of chronic disease. Your first indication that something is wrong might come from the results of a routine urine test (urinalysis). Glomerulonephritis signs and symptoms may include:
When to see a doctorMake an appointment with your health care provider promptly if you have signs or symptoms of glomerulonephritis. CausesMany conditions can cause glomerulonephritis. Sometimes the disease runs in families and sometimes the cause is unknown. Factors that can lead to inflammation of the glomeruli include the following conditions InfectionsInfectious diseases can directly or indirectly lead to glomerulonephritis. These infections include:
Autoimmune diseasesAutoimmune diseases are illnesses caused by the immune system attacking healthy tissues. Autoimmune diseases that may cause glomerulonephritis include:
VasculitisVasculitis is inflammation of blood vessels. Types of vasculitis that can cause glomerulonephritis include:
Sclerotic conditionsSome diseases or conditions cause scarring of the glomeruli that results in poor and declining kidney function. These include:
Other causesInfrequently, chronic glomerulonephritis runs in families. One inherited form, Alport syndrome, also might impair hearing or vision. Glomerulonephritis is associated with certain cancers, such as gastric cancer, lung cancer and chronic lymphocytic leukemia. ComplicationsGlomerulonephritis affects the ability of nephrons to filter the bloodstream efficiently. The breakdown in filtering results in:
Possible complications of glomerulonephritis include:
PreventionThere may be no way to prevent some forms of glomerulonephritis. However, here are some steps that might be beneficial:
Feb. 26, 2022 What is a known clinical manifestation in Poststreptococcal glomerulonephritis?Clinical features
Edema (often pronounced facial and orbital edema, especially on arising in the morning) Hypertension. Proteinuria. Macroscopic hematuria, with urine appearing dark, reddish-brown. Complaints of lethargy, generalized weakness, or anorexia.
Which is a clinical manifestation of glomerulonephritis?Glomerulonephritis signs and symptoms may include: Pink or cola-colored urine from red blood cells in your urine (hematuria) Foamy or bubbly urine due to excess protein in the urine (proteinuria) High blood pressure (hypertension)
What happens in post streptococcal glomerulonephritis?Poststreptococcal GN causes the tiny blood vessels in the filtering units of the kidneys (glomeruli) to become inflamed. This makes the kidneys less able to filter the urine. The condition is not common today because infections that can lead to the disorder are treated with antibiotics.
What type of reaction is post streptococcal glomerulonephritis?Excerpt. Poststreptococcal glomerulonephritis (PSGN) is characterized by rapid deterioration of kidney functions due to an inflammatory response (type III hypersensitivity reaction) following streptococcal infection.
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