Which cell size is the most efficient at exchanging materials with the environment?

Why are cells so small? And why are we made of so many? It seems like it would be easier to be made of 100 or even 1,000 cells instead of trillions. One of the reasons we teach students that cells are small is because they need a large surface area to volume ratio. The larger the ratio, the more efficient the cell is at moving materials in and out of the cell.

I’ve seen cell size labs that use different sized agar cubes prepared with a pH indicator. The cubes start pink and lose their color as they soak. (Here is a free version from Flinn if you are feeling ambitious!) Frankly with 3 preps a day this year, I didn’t have the time or energy to pour agar cubes. Instead I found a quick and easy way for students to see the same concept- using beets and bleach.

In this experiment, cut different sized beet cubes, a small, a medium, and a large. The students soak the cubes in bleach for roughly 30 minutes (I had them doing some practice SA:V calculations while they waited). Tip: if you use tupperware containers with lids you won’t have to smell bleach fumes all day, or you can put parafilm over the beakers.

After 30 minutes of soaking, students remove the beets, cut them open, and measure the amount of red pigment remaining. It is an easy way to see that small cells are more efficient at moving materials in and out. If you are interested in seeing the lab write-up I wrote, you can view it here.
I hope your students enjoy it!

The Elements of Life

In biology, the elements of life are the essential building blocks that make up living things. They are carbon, hydrogen, nitrogen, oxygen, phosphorus, and sulfur. The first four of these are the most important, as they are used to construct the molecules that are necessary to make up living cells. These elements form the basic building blocks of the major macromolecules of life, including carbohydrates, lipids, nucleic acids and proteins. Carbon is an important element for all living organisms, as it is used to construct the basic building blocks of life, such as carbohydrates, lipids, and nucleic acids. Even the cell membranes are made of proteins. Carbon is also used to construct the energy-rich molecules adenosine triphosphate (ATP) and guanosine triphosphate (GTP). Hydrogen is used to construct the molecules water and organic compounds with carbon. Hydrogen is also used to construct ATP and GTP. Nitrogen is used to construct the basic building blocks of life, such as amino acids, nucleic acids, and proteins. It is also used to construct ATP and GTP. Oxygen is used to construct the basic building blocks of life, such as carbohydrates, lipids, and nucleic acids. It is also used to construct ATP and GTP. Phosphorus is used to construct the basic building blocks of life, such as carbohydrates, lipids, and nucleic acids.

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  • Learning Objectives
    • Describe the factors limiting cell size and the adaptations cells make to overcome the surface area to volume issue

    At 0.1 to 5.0 μm in diameter, prokaryotic cells are significantly smaller than eukaryotic cells, which have diameters ranging from 10 to 100 μm. The small size of prokaryotes allows ions and organic molecules that enter them to quickly diffuse to other parts of the cell. Similarly, any wastes produced within a prokaryotic cell can quickly diffuse out. This is not the case in eukaryotic cells, which have developed different structural adaptations to enhance intracellular transport.

    Figure \(\PageIndex{1}\): Relative Size of Atoms to Humans: This figure shows relative sizes on a logarithmic scale (recall that each unit of increase in a logarithmic scale represents a 10-fold increase in the quantity being measured).

    In general, small size is necessary for all cells, whether prokaryotic or eukaryotic. Consider the area and volume of a typical cell. Not all cells are spherical in shape, but most tend to approximate a sphere. The formula for the surface area of a sphere is 4πr2, while the formula for its volume is 4πr3/3. As the radius of a cell increases, its surface area increases as the square of its radius, but its volume increases as the cube of its radius (much more rapidly).

    Therefore, as a cell increases in size, its surface area-to-volume ratio decreases. This same principle would apply if the cell had the shape of a cube (below). If the cell grows too large, the plasma membrane will not have sufficient surface area to support the rate of diffusion required for the increased volume. In other words, as a cell grows, it becomes less efficient. One way to become more efficient is to divide; another way is to develop organelles that perform specific tasks. These adaptations lead to the development of more sophisticated cells called eukaryotic cells.

    Figure \(\PageIndex{1}\): Surface Area to Volume Ratios: Notice that as a cell increases in size, its surface area-to-volume ratio decreases. When there is insufficient surface area to support a cell’s increasing volume, a cell will either divide or die. The cell on the left has a volume of 1 mm3 and a surface area of 6 mm2, with a surface area-to-volume ratio of 6 to 1, whereas the cell on the right has a volume of 8 mm3 and a surface area of 24 mm2, with a surface area-to-volume ratio of 3 to 1.

    Smaller single-celled organisms have a high surface area to volume ratio, which allows them to rely on oxygen and material diffusing into the cell (and wastes diffusing out) in order to survive. The higher the surface area to volume ratio they have, the more effective this process can be. Larger animals require specialized organs (lungs, kidneys, intestines, etc.) that effectively increase the surface area available for exchange processes, and a circulatory system to move material and heat energy between the surface and the core of the organism.

    Increased volume can lead to biological problems. King Kong, the fictional giant gorilla, would have insufficient lung surface area to meet his oxygen needs, and could not survive. For small organisms with their high surface area to volume ratio, friction and fluid dynamics (wind, water flow) are relatively much more important, and gravity much less important, than for large animals.

    However, increased surface area can cause problems as well. More contact with the environment through the surface of a cell or an organ (relative to its volume) increases loss of water and dissolved substances. High surface area to volume ratios also present problems of temperature control in unfavorable environments.

    Contributions and Attributions

    • OpenStax College, Biology. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44404/latest...ol11448/latest. License: CC BY: Attribution
    • Robert Bear and David Rintoul, Introduction to Cells. October 23, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m47170/latest/. License: CC BY: Attribution
    • eukaryotic. Provided by: Wiktionary. Located at: http://en.wiktionary.org/wiki/eukaryotic. License: CC BY-SA: Attribution-ShareAlike
    • cell. Provided by: Wiktionary. Located at: http://en.wiktionary.org/wiki/cell. License: CC BY-SA: Attribution-ShareAlike
    • prokaryotic. Provided by: Wiktionary. Located at: http://en.wiktionary.org/wiki/prokaryotic. License: CC BY-SA: Attribution-ShareAlike
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    • OpenStax College, Biology. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44405/latest...ol11448/latest. License: CC BY: Attribution
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    • OpenStax College, Studying Cells. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44405/latest...1_01ab_new.jpg. License: CC BY: Attribution
    • OpenStax College, Biology. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44405/latest...ol11448/latest. License: CC BY: Attribution
    • General Biology/Cells/Cell Structure. Provided by: Wikibooks. Located at: en.wikibooks.org/wiki/General...%23Cell_Theory. License: CC BY-SA: Attribution-ShareAlike
    • cell theory. Provided by: Wiktionary. Located at: en.wiktionary.org/wiki/cell_theory. License: CC BY-SA: Attribution-ShareAlike
    • OpenStax College, Introduction. October 16, 2013. Provided by: OpenStax CNX. Located at: http://cnx.org/content/m44404/latest...e_04_00_00.jpg. License: CC BY: Attribution
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    • Diagram of an animal cell in three dimensions. Provided by: Wikimedia. Located at: commons.wikimedia.org/wiki/Fi...dimensions.png. License: Public Domain: No Known Copyright
    • Cell Size. Provided by: OpenStax CNX. Located at: http://cnx.org/contents/. License: CC BY-SA: Attribution-ShareAlike
    • Surface Area to Volume Ratios. Provided by: Wikipedia. Located at: en.Wikipedia.org/wiki/Surface-area-to-volume_ratio. License: CC BY-SA: Attribution-ShareAlike
    • Surface area. Provided by: Wiktionary. Located at: en.wiktionary.org/wiki/surface_area. License: CC BY-SA: Attribution-ShareAlike
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    • Diagram of an animal cell in three dimensions. Provided by: Wikimedia. Located at: commons.wikimedia.org/wiki/Fi...dimensions.png. License: Public Domain: No Known Copyright
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    Key Points

    • As a cell grows, its volume increases much more rapidly than its surface area. Since the surface of the cell is what allows the entry of oxygen, large cells cannot get as much oxygen as they would need to support themselves.
    • As animals increase in size they require specialized organs that effectively increase the surface area available for exchange processes.

    Key Terms

    • surface area: The total area on the surface of an object.

    Which cell shape is the most efficient exchange of materials?

    The sphere has a larger surface area to volume ratio and would exchange chemicals with the environment more efficiently to support its volume, even though the cube has a larger surface area.

    Which size cells are most efficient?

    Small cells are most efficient at taking up oxy- gen and nutrients from the environment. (Note that they are also able to release waste carbon dioxide more efficiently.) 4.

    Which cell would likely be more efficient at exchanging substances with the surrounding environment?

    Smaller cells typically have a higher surface area-to-volume ratio and more efficient exchange of materials with the environment.

    Which cell size is the most efficient at exchanging materials with the environment quizlet?

    A small cell would be more efficient at exchange of materials from its surrounding environment as once material enters the cell it would be more evenly distributed internally.