Excess intracellular iron is toxic to cells (iron-induced toxicity). Ferritin is an intracellular iron storage protein that binds excess iron. The presence of ferritin can protect cells from iron-induced toxicity. Show
In an experiment to investigate the effects of dietary iron intake on ferritin synthesis, rats were given food containing different amounts of iron. Subsequently, the levels of ferritin protein in the liver were measured. The results are shown in Figure 1. Based on these and other data, researchers have developed the following model demonstrating how ferritin synthesis is regulated by iron. When iron levels are low, a repressor of translation, iron response protein (IRP), binds to an iron response element (IRE), which is a stem-loop structure near the 5¢ end of ferritin mRNA. When iron levels are high, intracellular iron binds to the IRP, and the iron-IRP complex dissociates from the IRE, permitting ribosomes to proceed with the translation of ferritin mRNA. Figure 2 represents the model of the regulation of ferritin mRNA translation by iron. Figure 2. Model of regulation of ferritin synthesis by iron Based on the model of ferritin synthesis presented in Figure 2, which of the following describes the role of feedback on the control of intracellular iron levels? What is the role of cyclic AMP in the signal transduction pathway?Cyclic AMP (cAMP)
In response to signals, an enzyme called adenylyl cyclase converts ATP into cAMP, removing two phosphates and linking the remaining phosphate to the sugar in a ring shape.
What is the role of cAMP in a signal transduction pathway quizlet?What is the role of cAMP in a signal transduction pathway? Correct This answer choice is correct because cAMP is a second messenger; it carries a signal from the G protein-coupled receptors to the beginning of the phosphorylation cascade.
What is the role of cyclic AMP cAMP in the liver signal transduction pathway activated by epinephrine?The G protein activates an enzyme called adenylyl cyclase. When activated, adenylyl cyclase converts a large number of ATP molecules into signaling molecules, called cyclic AMP (cAMP). Because cAMP carries the message of the first messenger (epinephrine) into the cell, cAMP is referred to as a second messenger.
What is the role of cyclic AMP or calcium ions in signal transduction quizlet?For example, a second messenger called cyclic AMP carries the signal initiated by epinephrine from the plasma membrane of a liver cell or muscle cell into the cell's interior, where the signal eventually brings about glycogen breakdown.
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Which of the following best describes the role of cyclic AMP in the signal transduction pathway?
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