Question 11 / 1 ptsThe nurse is caring for a patient who has recurrent wound infections. The patient’s currentinfection is not responding to an antibiotic that has been used successfully several times in thepast. The nurse understands that this is most likely due to:Correct!acquired bacterial resistance.cross-resistance.inherent bacterial resistance.transferred resistance. Show
Question 21 / 1 ptsThe nurse is preparing to administer the first dose of an antibiotic to a patient admitted for aurinary tract infection. Which action is most important prior to administering the antibiotic? Get answer to your question and much more Question 31 / 1 ptsThe nurse is teaching a patient who will be discharged home from the hospital to takeamoxicillin (Amoxil) twice daily for 10 days. Which statement by the nurse is correct? Get answer to your question and much more General High Alert Medication: This medication bears a heightened risk of causing significant patient harm when it is used in error. Genetic Implications: Pronunciation: Trade Name(s)
Ther. Class. antianginals antihypertensives Pharm. Class. beta blockers Indications
Unlabeled Use(s):
Action Blocks stimulation of beta1 (myocardial)-adrenergic receptors. Does not usually affect beta2 (pulmonary, vascular, uterine)-adrenergic receptor sites. Therapeutic Effect(s):
PharmacokineticsAbsorption: Well absorbed after oral administration. Distribution: Crosses the blood-brain barrier, crosses the placenta; small amounts enter breast milk. Metabolism and Excretion: Mostly metabolized by the liver (primarily by CYP2D6; the CYP2D6 enzyme system exhibits genetic polymorphism); ~7% of population may be poor metabolizers and may have significantly ↑ metoprolol concentrations and an ↑ risk of adverse effects. Half-life: 3–7 hr. TIME/ACTION PROFILE (cardiovascular effects)
Contraindication/PrecautionsContraindicated in:
Use Cautiously in:
Adverse Reactions/Side EffectsCV: BRADYCARDIA, HF, PULMONARY EDEMA, hypotension, peripheral vasoconstriction Derm: rash EENT: blurred vision, stuffy nose Endo: hyperglycemia, hypoglycemia GI: constipation, diarrhea, drug-induced hepatitis, dry mouth, flatulence, gastric pain, heartburn, ↑ liver enzymes, nausea, vomiting GU: erectile dysfunction, ↓ libido, urinary frequency MS: arthralgia, back pain, joint pain Neuro: fatigue, weakness, anxiety, depression, dizziness, drowsiness, insomnia, memory loss, mental status changes, nervousness, nightmares Resp: bronchospasm, wheezing Misc: drug-induced lupus syndrome * CAPITALS indicate life-threatening. InteractionsDrug-Drug
Route/DosageWhen switching from immediate-release to extended-release product, the same total daily dose can be used PO (Adults): Hypertension/angina– 25–100 mg/day as a single dose initially or 2 divided doses; may be ↑ every 7 days as needed up to 450 mg/day (immediate-release) or 400 mg/day (extended-release) (for angina, give in divided doses). Extended-release products are given once daily. MI– 25–50 mg (starting 15 min after last IV dose) every 6 hr for 48 hr, then 100 mg twice daily. Heart failure– 12.5–25 mg once daily (of extended-release), can be doubled every 2 wk up to 200 mg/day. Migraine prevention– 50–100 mg 2–4 times daily (unlabeled). IV (Adults): MI– 5 mg every 2 min for 3 doses, followed by oral dosing. PO (Children ≥6 yr): Hypertension– 1 mg/kg once daily (extended-release capsules); may be titrated, as needed (not to exceed 50 mg/day). Availability (generic available)Tablets (tartrate): 25 mg, 37.5 mg, 50 mg, 75 mg, 100 mg Cost: Generic: All strengths $7.18/100 Extended-release capsules (succinate; Kapspargo Sprinkle): 25 mg, 50 mg, 100 mg, 200 mg Extended-release tablets (succinate; Toprol XL): 25 mg, 50 mg, 100 mg, 200 mg Cost: Generic: 25 mg $35.68/100, 50 mg $41.93/100, 100 mg $53.95/100, 200 mg $84.54/100 Solution for injection: 1 mg/mL In Combination with: hydrochlorothiazide (Dutoprol, Lopressor HCT). See combination drugs. Assessment
Lab Test Considerations: May cause ↑ BUN, serum lipoprotein, potassium, triglyceride, and uric acid levels.
Implementation
IV Administration
Patient/Family Teaching
Evaluation/Desired Outcomes
metoprolol is a sample topic from the Davis's Drug Guide. To view other topics, please log in or purchase a subscription. Nursing Central is an award-winning, complete mobile solution for nurses and students. Look up information on diseases, tests, and procedures; then consult the database with 5,000+ drugs or refer to 65,000+ dictionary terms. Complete Product Information. Which adverse effect can result if tetracycline is administered?Common side effects include gastrointestinal upset, nausea, poor appetitle, diarrhea, glossitis, rash and hypersensitivity reactions. Tetracycline can cause staining of developing teeth (in children or when taken by a pregnant mother).
Can I stop doxycycline early?Carry on taking doxycycline until you've completed the course, even if you feel better. If you stop your treatment early, the infection could come back, or you may no longer be protected against malaria.
Which adverse effect can result if tetracycline is administered to children younger than 8 years?Do not give tetracyclines to infants or children 8 years of age and younger unless directed by your doctor. Tetracyclines may cause permanently discolored teeth and other problems in patients in these age groups.
Which of the following conditions occurs when normal flora is disturbed during antibiotic therapy?Selective pressure occurs when the administration of an antibiotic decreases the numbers of normal flora, allowing resistant bacteria to proliferate.
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