Which factor should you note is most significant for the development of cancer?

Adam E, Kaufman RH, Adler-Storthz K, et al.
A prospective study of association of herpes simplex virus and human
papillomavirus infection with cervical neoplasia in women exposed to
diethylstilbestrol in utero. Int J Cancer. 1985;35:19-26.

Castellsagué X, Díaz M, Vaccarella S, de Sanjosé S, Muñoz N, Herrero R, et al. Intrauterine device use,
cervical infection with human papillomavirus, and risk of cervical cancer: A
pooled analysis of 26 epidemiological studies. Lancet Oncol.
2011;12(11):1023.

 Centers for Disease Control and Prevention (CDC). Use of 9-Valent Human Papillomavirus

(HPV) Vaccine: Updated HPV Vaccination Recommendations of the Advisory
Committee on Immunization Practices. MMWR Morb Mortal Wkly Rep. 2015
March 27;64(11):300−304.

Chih HJ, Lee AH, Colville L, Binns CW, Xu D. A review of dietary prevention of human papillomavirus-related infection of the cervix and
cervical intraepithelial neoplasia. Nutr Cancer. 2013;65:317–328.

Cohen PA, Jhingran A, Oaknin A, Denny L. Cervical cancer. Lancet.
2019 Jan 12;393(10167):169-182. doi: 10.1016/S0140-6736(18)32470-X.

Cortessis VK, Barrett M, Brown Wade N, Enebish T, Perrigo JL, Tobin J, et al.
Intrauterine Device Use and Cervical Cancer Risk: A Systematic Review and
Meta-analysis. Obstet Gynecol. 2017;130(6):1226.

 Eifel P, Klopp AH, Berek JS, and Konstantinopoulos A. Chapter 74: Cancer of the Cervix, Vagina, and Vulva. In: DeVita VT, Lawrence TS, Rosenberg SA, eds. DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology. 11th ed. Philadelphia, Pa: Lippincott Williams & Wilkins; 2019.

Fonseca-Moutinho JA. Smoking and cervical cancer. ISRN Obstet Gynecol. 2011;2011:847684. doi:10.5402/2011/847684.

Frumovitz M. Invasive cervical cancer: Epidemiology, risk factors, clinical manifestations, and
diagnosis. UpToDate website. https://www.uptodate.com/contents/invasive-cervical-cancer-epidemiology-risk-factors-clinical-manifestations-and-diagnosis. Updated June 26, 2019. Accessed October 25, 2019.

 Ghosh C, Baker JA, Moysich KB, et al. Dietary intakes of selected nutrients and food groups and risk of cervical cancer. Nutr Cancer. 2008;60:331-341.

Hatch EE, Herbst AL, Hoover RN, et al. Incidence of squamous neoplasia of the cervix and vagina in women exposed
prenatally to diethylstilbestrol (United States). Cancer Causes Control. 2001;12:837-845.

Hernandez BY, Wilkens LR, Zhu X, et al. Transmission of human papillomavirus in heterosexual couples. Emerg Infect Dis. 2008;14(6):888−894.

Hogewoning CJ, Bleeker MC, van den Brule AJ, et al. Condom use promotes regression of cervical intraepithelial neoplasia and clearance of human papillomavirus: A randomized clinical trial. Int J Cancer. 2003;107(5):811−816.

Hoover RN, Hyer M, Pfeiffer RM, et al. Adverse health outcomes in women exposed in utero to diethylstilbestrol. N Engl J Med. 2011.
365: 1304-14.

International Collaboration of Epidemiological Studies of Cervical Cancer. Appleby P, Beral V, Berrington de González
A, et al. Cervical cancer and hormonal contraceptives: Collaborative reanalysis of individual data for 16,573 women with cervical cancer and 35,509 women without cervical cancer from 24 epidemiological studies. Lancet. 2007;370:1609-1621.

International Collaboration of Epidemiological Studies of Cervical Cancer. Comparison of risk factors for invasive squamous cell carcinoma and adenocarcinoma of the cervix: collaborative reanalysis of individual data on 8,097 women with squamous cell carcinoma and 1,374 women with adenocarcinoma from 12 epidemiological studies. Int J Cancer. 2007 Feb 15;120(4):885-91.

Jhungran A, Russell AH, Seiden MV, Duska LR, Goodman A, Lee S,et al. Chapter 84: Cancers of the Cervix, Vulva, and Vagina. In: Niederhuber
JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. Abeloff’s Clinical Oncology. 6th ed. Philadelphia, Pa: Elsevier; 2020.

Lu B, Wu Y, Nielson CM, et al. Factors associated with acquisition and clearance of human papillomavirus infection in a cohort of US men: a prospective study. J Infect Dis. 2009;199(3):362−371.

National Cancer Institute. Physician Data Query (PDQ). Cervical Cancer Treatment – Health Professional Version. 2019. https://www.cancer.gov/types/cervical/hp/cervical-treatment-pdq. Updated February 6, 2019. Accessed on September 5, 2019.

National Comprehensive Cancer Network (NCCN). Clinical Practice Guidelines in Oncology: Cervical Cancer.
Version 4.2019. Accessed at https://www.nccn.org/professionals/physician_gls/pdf/cervical.pdf on September 5, 2019.

Roura E, Castellsagué, X, Pawlita M, et al. Smoking as a major risk factor for cervical cancer and pre-cancer: Results from the EPIC cohort. Int J Cancer. 2014; 135: 453–66.

Schiffman M, Castle PE, Jeronimo J, et al. Human papillomavirus and cervical cancer. Lancet. 2007;370(9590):890−907.

Silva J, Cerqueira F, Medeiros R. Chlamydia trachomatis infection: implications for HPV status and cervical cancer. Arch Gynecol Obstet. 2014 Apr;289(4):715-23. doi: 10.1007/s00404-013-3122-3.

Tokudome S, Suzuki S, Ichikawa H, et al.  Cancer risk in women prenatally exposed to diethylstilbestrol. Int J Cancer. 2007;121:356-360.

Winer RL, Hughes JP, Feng Q, et al. Condom use and the risk of genital human papillomavirus infection in young women. N Engl J Med. 2006;354:2645−2654.

Winer RL, Lee SK, Hughes JP, et al. Genital human papillomavirus infection: incidence and risk factors in a cohort of female university students. Am J Epidemiol. 2003;157(3):218-226. Erratum in: Am J Epidemiol. 2003;157(9):858.

Zhu H, Shen Z, Luo H, Zhang W, Zhu X. Chlamydia Trachomatis Infection-Associated Risk of Cervical Cancer: A Meta-Analysis. Medicine (Baltimore). 2016;95(13):e3077. doi:10.1097/MD.0000000000003077

What is the main cause of cancer?

Cancer is caused by certain changes to genes, the basic physical units of inheritance. Genes are arranged in long strands of tightly packed DNA called chromosomes. Cancer is a genetic disease—that is, it is caused by changes to genes that control the way our cells function, especially how they grow and divide.

Which of the following are associated with development of cancer?

Age, weight, exposure to carcinogens, and genetics can increase the risk of developing cancer.

What are the top 10 causes of cancer?

Contents.
1 Genetics. 1.1 Cancer syndromes..
2 Physical and chemical agents. 2.1 Smoking. 2.2 Materials..
3 Lifestyle. 3.1 Alcohol. 3.2 Diet. ... .
4 Hormones..
5 Infection and inflammation. 5.1 Viruses. 5.2 Bacteria and parasites. ... .
6 Radiation. 6.1 Non-ionizing radiation. ... .
7 Rare causes. 7.1 Organ transplantation. ... .
8 References..

Which behavior is most likely to increase your chance of developing a cancer?

These include using tobacco and alcohol, being overweight, and getting multiple sunburns. Other risk factors cannot be avoided, such as getting older. Learn about the risk factors for certain types of cancer.