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Carlos Martinez, Stephen Rietbrock, Lesley Wise, Deborah Ashby, Jonathan Chick, Jane Moseley, Stephen Evans and David Gunnell BMJ: British Medical Journal Vol. 330, No. 7488 (Feb. 19, 2005) , pp. 389-393 (5 pages) Published By: BMJ https://www.jstor.org/stable/25458957 Read and download Log in through your school or library Alternate access options For independent researchers Read Online Read 100 articles/month free Subscribe to JPASS Unlimited reading + 10 downloads Read Online (Free) relies on page scans, which are not currently available to screen readers. To access this article, please contact JSTOR User Support. We'll provide a PDF copy for your screen reader.With a personal account, you can read up to 100 articles each month for free. Get StartedAlready have an account? Log in Monthly Plan
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Log in through your institution Abstract Objective To compare the risk of non-fatal self harm and suicide in patients taking selective serotonin reuptake inhibitors (SSRIs) with that of patients taking tricyclic antidepressants, as well as between different SSRIs and different tricyclic antidepressants. Design Nested case-control study. Setting Primary care in the United Kingdom. Participants 146 095 individuals with a first prescription of an antidepressant for depression. Main outcome measures Suicide and non-fatal self harm. Results 1968 cases of non-fatal self harm and 69 suicides occurred. The overall adjusted odds ratio of non-fatal self harm was 0.99 (95% confidence interval 0.86 to 1.14) and that of suicide 0.57 (0.26 to 1.25) in people prescribed SSRIs compared with those prescribed tricyclic antidepressants. We found little evidence that associations differed over time since starting or stopping treatment. We found some evidence that risks of non-fatal self harm in people prescribed SSRIs compared with those prescribed tricyclic antidepressants differed by age group (interaction P = 0.02). The adjusted odds ratio of non-fatal self harm for people prescribed SSRIs compared with users of tricylic antidepressants for those aged 18 or younger was 1.59 (1.01 to 2.50), but no association was apparent in other age groups. No suicides occurred in those aged 18 or younger currently or recently prescribed tricyclic antidepressants or SSRIs. Conclusion We found no evidence that the risk of suicide or non-fatal self harm in adults prescribed SSRIs was greater than in those prescribed tricyclic antidepressants. We found some weak evidence of an increased risk of non-fatal self harm for current SSRI use among those aged 18 or younger. However, preferential prescribing of SSRIs to patients at higher risk of suicidal behaviour cannot be ruled out. Journal Information The BMJ is an international peer reviewed medical journal and a fully "online first" publication. Our publishing model–"continuous publication"– means that all articles appear on bmj.com before being included in an issue of the print journal. The website is updated daily with the BMJ's latest original research, education, news, and comment articles, as well as podcasts, videos, and blogs. All the BMJ's original research is published in full on bmj.com, with open access and no limits on word counts. We do not charge authors or readers for research articles, nor for other articles arising from work funded by open access grants. The BMJ's vision is to be the world's most influential and widely read medical journal. Our mission is to lead the debate on health and to engage, inform, and stimulate doctors, researchers, and other health professionals in ways that will improve outcomes for patients. We aim to help doctors to make better decisions. The BMJ team is based mainly in London, although we also have editors elsewhere in Europe and in the US. Digitization of the British Medical Journal and its forerunners (1840-1996) was completed by the U.S. National Library of Medicine (NLM) in partnership with The Wellcome Trust and the Joint Information Systems Committee (JISC) in the UK. This content is also freely available on PubMed Central. Publisher Information Vision – To be the world's leading and most trusted provider of information and services that will make a real difference in clinical practice and improve outcomes for patients. Mission – To lead the debate on healthcare and to deliver innovative, useful evidence based knowledge, best practice and learning to doctors, other health professionals, researchers and patients when and where they need it. We publish a number of journals covering major specialties and a growing number of online products for doctors and patients. Continuous product development ensures that our products and services are of constant importance to the medical profession. The BMJ Publishing Group Ltd (BMJPG) is the innovative publishing division of the British Medical Association (BMA) and is one of the world leaders in medical publishing. The BMJ Group complements the activities of the BMA. Rights & Usage This item is part of a JSTOR Collection. Which kind of drug is most closely associated with increasing the availability of serotonin?SSRIs increase the amount of serotonin available to the brain, and are commonly prescribed for depression.
Which of the following is seen as an effective treatment for severe depression that does not respond to drug therapy?Electroconvulsive therapy (ECT) is useful for patients who are not responding well to medications or are suicidal. ECT is an effective treatment for patients who do not respond to drug therapy, are psychotic, or are suicidal or dangerous to themselves.
In which type of biomedical therapy does a therapist Send a brief electrical current through the brain of an anesthetized patient?What is Electroconvulsive Therapy (ECT)? Electroconvulsive therapy (ECT) is a medical treatment most commonly used in patients with severe major depression or bipolar disorder that has not responded to other treatments. ECT involves a brief electrical stimulation of the brain while the patient is under anesthesia.
Which of the following types of therapy is best known for being non directive?What Is Client-Centered Therapy? Client-centered therapy, also known as person-centered therapy or Rogerian therapy, is a non-directive form of talk therapy developed by humanist psychologist Carl Rogers during the 1940s and 1950s.
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Carlos has been prescribed an ssri to treat his illness. this type of drug is classified as a(n)
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