Based solely on this information, which person would be most likely to experience sleep apnea?

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  • Based solely on this information, which person would be most likely to experience sleep apnea?

Adults with sleep apnea are more likely to experience involuntary job loss

SAN ANTONIO – June 12, 2019 – Recently unemployed people with undiagnosed obstructive sleep apnea have a higher risk of having lost a job multiple times, according to preliminary results from a new study.

Results show that individuals with undiagnosed obstructive sleep apnea were more likely to have experienced multiple involuntary job losses. Compared to participants who did not have sleep apnea, those with moderate-to-severe sleep apnea were more than twice as likely to have a history of multiple job layoffs or firings.

“These results suggest that undetected obstructive sleep apnea could have long-term, negative effects on vocational functioning,” said principal investigator Patricia Haynes, Ph.D., an associate professor in the Department of Health Promotion Sciences at the University of Arizona in Tucson.

Nearly 30 million adults in the U.S. have obstructive sleep apnea, a chronic disease that involves the repeated collapse of the upper airway during sleep. Common warning signs include snoring, choking or gasping during sleep. Untreated sleep apnea can cause excessive daytime sleepiness, fatigue, and impairments in cognitive functioning.

This analysis of data from the ongoing, prospective Assessing Daily Activity Patterns through occupational Transitions (ADAPT) study involved 261 participants with an average age of 41 years; 58% were women. Seventy-three percent received hourly wages rather than a salary, and about 45% of participants had a history of multiple job losses. Breathing during sleep was evaluated with a home sleep apnea test, which revealed that 42% percent had at least mild sleep apnea.

After a propensity score analysis, 39 matched pairs (78 participants) remained for the logistic regression model. Results were controlled for potential confounders such as age, sex, race, and job payment type.

The authors noted that one limitation of the study was the inability to include body mass index in the analysis.

The research abstract was published recently in an online supplement of the journal Sleep and was presented Sunday, June 9, in San Antonio at SLEEP 2019, the 33rd annual meeting of the Associated Professional Sleep Societies LLC (APSS), which is a joint venture of the American Academy of Sleep Medicine and the Sleep Research Society.

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This study was supported by funding from the National Heart, Lung, and Blood Institute of the National Institutes of Health.

Abstract Title: Individuals with Obstructive Sleep Apnea have Higher Likelihood of Multiple Involuntary, Job Losses
Abstract ID: 0484
Presentation Date: Sunday, June 9
Poster Presentation: 5:15 p.m. to 7:15 p.m., Board 139

For a copy of the abstracts or to arrange an interview with a study author or an AASM spokesperson, please contact the AASM media relations staff at 630-737-9700 or .

About the American Academy of Sleep Medicine
Established in 1975, the American Academy of Sleep Medicine (AASM) improves sleep health and promotes high quality, patient-centered care through advocacy, education, strategic research, and practice standards. The AASM has a combined membership of 10,000 accredited member sleep centers and individual members, including physicians, scientists and other health care professionals. For more information about sleep and sleep disorders, including a directory of AASM-accredited member sleep centers, visit www.sleepeducation.org.

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Study shows that people with sleep apnea have a high risk of death

WESTCHESTER, Ill. – A study in the August 1 issue of the journal Sleep shows that people with severe sleep apnea have a much higher mortality risk than people without sleep apnea, and this risk of death increases when sleep apnea is untreated.

Results show that people who have severe sleep apnea, which involves frequent breathing pauses during sleep, have three times the risk of dying due to any cause compared with people who do not have sleep apnea. This sleep apnea risk is represented by an adjusted hazard ratio of 3.2 after controlling for age, sex and body mass index. When 126 participants who reported regular use of continuous positive airway pressure (CPAP) therapy were removed from the statistical analysis, the hazard ratio for all-cause mortality related to severe sleep apnea rose to 4.3.

“We found that both men and women with sleep apnea in the general population – not patients – mostly undiagnosed and untreated, had poorer survival compared with persons without sleep apnea, given equal BMI, age and sex,” said principal investigator and lead author Terry Young, PhD, professor of epidemiology at the University of Wisconsin-Madison.

According to Young, most previous studies of sleep apnea and mortality have involved patients referred for a clinical sleep diagnostic evaluation; the mortality risk for sleep apnea in the general population has not been previously reported.

The study was an 18-year follow-up of 1,522 participants in the ongoing Wisconsin Sleep Cohort Study, which was established in 1988 and involved a random sample of men and women from the community who were between the ages of 30 and 60 when the study began. After spending one night at the University of Wisconsin General Clinical Research Center for assessment by polysomnography, participants were categorized by apnea-hypopnea index (AHI), which is the average number of breathing pauses (apneas) and reductions (hypopneas) per hour of sleep. Sixty-three individuals (about four percent) had severe sleep apnea at baseline with an AHI of 30 or more and a range of 30 to 97 apneas and hypopneas per hour. About 76 percent of the study group (1,157 individuals) had no sleep apnea with an AHI of less than five.

For the follow-up study, state and national death records were reviewed up to March 1, 2008, to identify participants who had died and to note the causes of death listed on the death certificates. Eighty deaths were recorded, including 37 deaths attributed to cancer and 25 deaths attributed to cardiovascular disease and stroke.

About 19 percent of participants with severe sleep apnea died (12 deaths), compared with about four percent of participants with no sleep apnea (46 deaths). Although participants with mild sleep apnea (AHI of five to 14) or moderate sleep apnea (AHI of 15 to 29) had a mortality risk that was 50 percent greater than those with no sleep apnea, the results did not achieve statistical significance.

Hazard ratios for all-cause mortality remained high after further adjustments for other factors such as smoking, alcohol use, sleep duration and total cholesterol.   Severe sleep apnea was associated with increased mortality whether or not participants experienced daytime sleepiness.

About 42 percent of deaths in people with severe sleep apnea (5 of 12 deaths) were attributed to cardiovascular disease or stroke, compared with 26 percent of deaths in people with no sleep apnea (12 of 46 deaths). When the 126 participants who reported regular CPAP use were removed from the analysis, the hazard ratio for cardiovascular mortality soared from 2.9 to 5.2 for people with severe sleep apnea. The results suggest that regular CPAP use may protect sleep apnea patients against cardiovascular death.

“I was surprised by how much the risks increased when we excluded people who reported treatment with CPAP,” Young said. “Our findings suggest – but cannot prove – that people diagnosed with sleep apnea should be treated, and if CPAP is the prescribed treatment, regular use may prevent premature death.”

Statistical adjustments show that high blood pressure, cardiovascular disease, stroke and diabetes may play a role in the association between sleep apnea and mortality, but the specific mechanisms by which sleep apnea contributes to mortality remain unclear.

The study was supported by grants from the National Institutes of Health.

According to the American Academy of Sleep Medicine, obstructive sleep apnea (OSA) involves a decrease or complete halt in airflow despite an ongoing effort to breathe. It occurs when the muscles relax during sleep, causing soft tissue in the back of the throat to collapse and block the upper airway.

The most common treatment for OSA is CPAP therapy, which provides a steady stream of air through a mask that is worn during sleep. This airflow keeps the airway open to prevent pauses in breathing and restore normal oxygen levels.

Sleep is the official journal of the Associated Professional Sleep Societies, LLC, a joint venture of the American Academy of Sleep Medicine and the Sleep Research Society.

For a copy of the study, “Sleep-Disordered Breathing and Mortality: Eighteen-Year Follow-Up of the Wisconsin Sleep Cohort,” or to arrange an interview with an AASM spokesperson, please contact the AASM at .

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